Presentation

It is one of the most powerful antioxidant enzymes, along with catalase and glutathione peroxidase.

In the body, SOD is associated with trace elements.

There are 3 types of function, depending on the site of activity and the metal with which it is associated:

• Intracellular SOD, bound to copper and zinc (Cu-Zn), protects polyunsaturated fatty acids from oxidation.
• Extracellular SOD, bound to copper and zinc, is involved in the protection of cellular matrix proteins.
• Intracellular SOD bound to manganese (Mn) converts oxygenated free radicals and protects against apoptosis (cell death).

Features and benefits

Its main properties derive from its antioxidant properties and are related to the prevention of the effects of ageing.

• Anti-aging
• Neurodegenerative diseases
• Anti-inflammatory joint
• Cardiovascular diseases
• Stress effects
• Skin aging
• Age-related macular degeneration
• Exercise: SOD would reduce lactic acid produced during endurance exercise

The different forms

We find SOD of plant origin: melon, maize, rice, wheat, tomato, pollen.

As a dietary supplement, classic SOD is most often derived from maize. For best absorption, it should be microencapsulated or placed in gastroresistant capsules. This prevents the breakdown of SOD by stomach acids.

The most active and studied SOD comes from melon: the patented Extramel® extract. This naturally microencapsulated SOD has a high enzymatic activity: 14,000 IU/g.

There is also GliSODin®, an Extramel® extract combined with a wheat protein called gliadin for better absorption. The disadvantage of this form is that gliadin is similar to gluten.

Dosage 

• Classic SOD: 100 to 200 mg per day
• Extramel®: 10 to 20 mg per day
• GliSODin®: 6.70 mg per day (this product is combined with other nutrients)

Prevention of age-related pathologies, stress: take the minimum dose
Age-related pathologies: take the maximum dose

Contraindications

In the absence of data, SOD supplementation is contraindicated in pregnant and lactating women and children.

The information and advice provided in this article is not intended to be a substitute for advice, diagnosis or prescription from a physician or other healthcare professional, who alone can adequately assess your health.