Family
- Apocynaceae
Constituents
- Saponins: mainly present in the leaves, the most important being gymnemic acid, which has the property of fighting sugar cravings
- Gurmarin: a protein that seems to have the same effect as gymnemic acid
- Fatty acids
- Sterols
- Flavonoids
Parts used
- All parts of this plant can be used, however, extracts are usually prepared from the leaves and, to a lesser extent, the roots.
Properties
- Decreases the absorption of sugar
- Improves insulin secretion
- Reduces sugar cravings
- Regulates appetite
- Protects cardiovascular (cholesterol)
- Reduces the level of fats (triglycerides and bad cholesterol) in the blood
- Protects the cardiovascular system from coronary heart disease
- Antioxidant action
- Reduces oxidative stress in diabetic individuals
- Stimulation of the immune system
- Antimicrobial activity
- Antibacterial action against E. Coli and Staphylococcus aureus
- antifungal action against the fungus Candida albicans
- antiviral action against the influenza virus
Indications
Contraindications
In the absence of data on long-term toxicity, the precautionary principle applies to pregnant and lactating women and children.
It is contraindicated in people with a history of liver disease.
It is also contraindicated 15 days before surgery.
In addition, there are interactions between this plant and certain medications, including:
- Certain antidiabetic medications (biguanides)
- Weight-loss medicines
- Cholesterol-lowering drugs
Side effects
As a rule, when the doses are respected, there are no noticeable side effects.
It is a safe and well-tolerated plant.
However, in case of overdose, some adverse effects can be observed and consist of hypoglycemia, confusion, fatigue, tremors, and sweating.
On the other hand, taken on an empty stomach, it can cause digestive symptoms such as nausea, stomach pains, and vomiting.
Dosage
Most studies recommend dosages of 400 mg/day (product titrated to at least 24% gymnemic acid) for diabetic patients to reduce blood glucose.
It is important, however, to know that there is no precise recommended dosage and that it varies greatly according to the indication, the galenic form, and the titrations of the active ingredients.
Therefore, it is essential to consult the seller's instructions, and if in doubt, talk to your doctor.